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Please use this identifier to cite or link to this item: http://hdl.handle.net/11173/2951

Title: 動脈硬化リスクとしての骨格筋量の減少
Other Titles: Decrease in skeletal muscle mass as an atherosclerosis risk factor
Authors: 和田, 萌希
堀田, 侑希
赤嶺, 百子
青, 未空
西河, 浩之
福永, 康智
谷口, 隆司
佐藤, 哲也
宮脇, 尚志
Wada, Moeki
Hotta, Yuuki
Akamine, Momoko
Ao, Misora
Nishikawa, Hiroyuki
Fukunaga, Yasutomo
Taniguchi, Takashi
Sato, Tetsuya
Miyawaki, Takashi
Keywords: skeletal muscle
body composition
health check-up
Issue Date: 26-Dec-2019
Publisher: 京都女子大学食物学会
Abstract: Objective: We investigated the relationship between skeletal muscle mass and atherosclerosis risks and determined a cut-off point of muscle mass percentage and atherosclerosis risk by gender. Methods: The study included 4,392 untreated men and 1,116 untreated women who underwent a health checkup. We obtained body composition, blood pressure and blood samples after an overnight fast. Skeletal muscle mass was assessed using a bioelectrical impedance method. Hypertension, dyslipidemia, and diabetes were defined as atherosclerosis risks. We used percentage of muscle mass as the skeletal muscle mass (%SM). Multiple linear regression analysis was performed for %SM, waist circumference, BMI, percentage of body fat, and age as independent variables, and the number of risks as a dependent variable. ROC analysis was performed to determine the cut-off point of %SM for determining two or more numbers of atherosclerosis risks. Results: The average levels of %SM in the subjects were 32.4±2.3% in men, and 26.4±2.3% in women, respectively. Multiple linear regression analysis showed that %SM significantly contributed to the risk for atherosclerosis, followed by age and BMI. ROC analysis showed that the optimal cut-off point of %SM was 32-33% in men and 25-26% in women for determining two or more numbers of atherosclerosis risks. Conclusions: It was suggested that there was a significant relation between a decrease in skeletal muscle mass and atherosclerosis, independent of body composition and age. We also noted a gender difference in terms of the relation of the level of muscle mass decrease and atherosclerosis risk.
URI: http://hdl.handle.net/11173/2951
Appears in Collections:第74号(2019-12-26)

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