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第61号(2006-12-10) >

このアイテムの引用には次の識別子を使用してください: http://hdl.handle.net/11173/1423

タイトル: マウス胸腺の抗体遺伝子転写細胞の分化
その他のタイトル: Differentiation of Immunoglobulin Gene-Transcribing Cells in the Thymus of the Mouse
著者: 安達, 綾希子
Adachi, Akiko
井上, 摩耶
Inoue, Maya
大野, 理絵
Ohno, Rie
城, 清佳
Joh, Sayaka
長尾, 美沙子
Nagao, Misako
宮田, 堅司
Miyata, Kenji
発行日: 10-Dec-2006
出版者: 京都女子大学食物学会
抄録: Immunoglobulin(Ig) heavy chain gene-transcribing cell diffrentiation was investigated in the thymus of BALB/c mice by the Realtime PCR for membrane-bound form IgM(IgM_m). The ratio of IgM_m to total IgM(IgM_t) was approximately 1 from fetus period to 14 days after the birth, and IgM transcriptions were almost processed to membrane-bound form. Then IgM_m transcriptions decreased and secretory form IgM(IgM_s), the difference between IgM_t and IgM_m, started being detected. It was concluded that thymus Ig gene-transcribing cells underwent the similar differential processes in which B cells developed from immature type having IgM_m to mature type secreting IgM_s, in secondary lymphoid tissues.
URI: http://hdl.handle.net/11173/1423


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