京都女子大学   京都女子大学図書館 English 日本語

Kyoto Women's University Academic Information Repository >
紀要論文(Bulletin Paper) >
食物学会誌 >
第67号(2013-01-31) >

このアイテムの引用には次の識別子を使用してください: http://hdl.handle.net/11173/122

タイトル: 転写方程式の分子論的解釈
その他のタイトル: Molecular Interpretation of Equation for Transcription
著者: 宮田, 堅司
Miyata, Kenji
キーワード: 転写
発行日: 31-Jan-2013
出版者: 京都女子大学食物学会
抄録: Considering the molecular mechanism, the equation for transcription, which describes the ratio of anygene-transcripts, is derived. RNA polymerase II moves from transcriptional starting point along a gene underaccelerative force F and resistant forces, both a frictional -rx˙ and -sx proportional to traveling distance x. Thenthe equation of motion of RNA polymerase II may be represented by the following, mx¨ = F - rx˙ - sx. In thisequation x, which means traveling distance of polymerase, may be considered as quantity of transcript, and that of inner standard gene is taken to be equal to unit, so that x can be regarded as the ratio of two gene-transcripts.Arranging the coefficients, the equation for transcription x¨ + 2ax˙ + bx = bD is obtained, where a = r/2m isexpected to be constant for any cases and D = F/bm to be almost same value for similar genes of same kinds ofcell. These predictions are examined for 9 kinds of interleukin.
URI: http://hdl.handle.net/11173/122


ファイル 記述 サイズフォーマット
0100_067_003.pdf820.28 kBAdobe PDF見る/開く



Powered by DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard - ご意見をお寄せください