http://hdl.handle.net/11173/581 2001-12-10 2026-04-19T09:37:16Z http://hdl.handle.net/11173/1397 タイトル: マウス胸腺における脂肪化および脂肪細胞分化 著者: 松永, 美沙子; Matsunaga, Misako; 江口, 晶紀子; Eguchi, Akiko; 田邊, 美和; Tanabe, Miwa; 山下, 真代; Yamashita, Masayo; 宮田, 堅司; Miyata, Kenji 抄録: The mouse thymus locates on a position close to the pericardial cavity and consists of two lobes. The lobes surrouded by a capsule are subdivided into many lobules by connective tissue trabeculae. Each lobule consists of lymphocytes-accumulated regions, cortex and medulla. In the previous study, since only lymphocytes in many kinds of thymus-constructing cell expressed the long type leptin receptor (OBRL), it was suggested that thymocytes were regulated with leptin produced by adipocytes differenciated and proliferated through thymic age involution. Then it is naturally interested in studying when lipogenesis and adipogenesis begin in the thymus either in embryogenesis or in postnatal growth. We extracted and measured the quantity of total lipid of the thymus and found that that began to increase at the period of 5 to 8 week-old after birth. The quantity of DNA of the thymus was little changed for this period. Then we directly observed histologically HE-stained sections under light microscope. The small number of adipocytes was observed at surrouding connective tissue, but never found in trabeculae of thymus of neonatal. In 5 week-old thymus adipocytes were first observed in small groups in the trabeculae. Secondly, we detected FGF10,PPARγ and leptin mENA expressions by the RTPCR method as the indication of adipogenesis in the thymus from embryo just before birth to 6 month-old. Both FGF10 and PPARγmRNA were detected in all specimens. The expression of PPARγ is slightly less than that of FGF10 in the embryonic thymus, but with incresing age it incresed and apparently more than that of FGF10 in the 6 moth-old thymus. These results suggest that adipogenesis in the thymus begins just before birth at the latest and that lipogenesis in the thymus does at 5 week-old after birth. 2001-12-09T15:00:00Z http://hdl.handle.net/11173/1398 タイトル: 老人の食生活の実態 著者: 河野, 篤子; Kohno, Atsuko 抄録: A survey of eating habits was conducted on the elderly persons living alone using the questionnaire and compared with those of persons living with their family. The result obtained are as follows : 1) Boild rice is the most frequently served diet for lunch and supper in both cases. Bread is served more frequently than boiled rice for breakfast. 2) For most kind of foods, serving frequencies were lower in elderly people living alone than those in people living with their family. 3) The intake of energy, protein and iron was significantly lower in people living than alone that of people living with their family, which is related to their lower intake of beans and vegitables. 4) The intake of iron is lower than "Recommended Dietary Allowance" in both cases. 2001-12-09T15:00:00Z http://hdl.handle.net/11173/1395 タイトル: 表紙ほか 2001-12-09T15:00:00Z http://hdl.handle.net/11173/1396 タイトル: 魚介類の脂質過酸化とPAF様リン脂質の生成 : 魚肉の部位や保存, 調理による影響 著者: 中山, 玲子; Nakayama, Reiko; 田中, じゅん; Tanaka, Jun; 吉田, 広佳; Yoshida, Hiroka 抄録: The relation of the lipid peroxidation and the generation of the PAF-like activities which exist in fishes were examined from the viewpoint of parts of the fish meats, storage and cooking. 1. PAF-like activity of the red muscle was remarkably higher than those of lean and fat muscles of tuna.Investigations of correlation between the PAF-like activities produced by peroxidation of CGP and contents of PUFA and alkyl ether-linked subclass in parent CGPs, revealed that the higher activity of red muscle were rich in alkyl ether-linked subclass and docosahexaenoate (DHA). 2. The generation of PAF-like activity and lipid peroxidation under saving of the meats of mackerel, were examined, using meats of just after the purchase, cold storage saving (at 4℃ for 4 days), and freezing (at -40℃ for 30 days). In the meat of the cold storage saving, the TBARS value was the highest, and the PAF-like activity was also the highest. The content of CGP of the meat decreased to about 50% of that of just after the purchase, and contents of alkyl ether-linked CGP increased about 4 times, by the cold storage.From these results, it was indicated that the enzymatic hydrolysis of CGP progressed under cold storage. 3. The PAF-like activities exist in the mackerel meats increased by the cooking (baked, fried), and the TBARS also showed high values. Although the vinegar cured mackerel is not heating cooking method, the PAF-like activity was the highest after 2 days. Furthermore, it became clear that the generation of PAF-like activity and lipid peroxidation were suppressed, when ginger and sesame were used in the cooking. 2001-12-09T15:00:00Z